Quantification of Cocaine Hydrochloride in Seized Drug Samples by Infrared Spectroscopy and PLSR

Detection of Cocaine in Seized Drug Samples by Capillary Electrophoresis Tandem Mass Spectrometry Authors

A methodology using capillary electrophoresis with tandem mass spectrometry detection (CE-MS/MS) was developed, and applied to determine the cocaine content of seized drugs. The cocaine separation among other concomitants by capillary electrophoresis was achieved in just 4.0 minutes using 30 mM ammonium formate, pH 6.5, as a background electrolyte (BGE). The correlation coefficient of the calib...

Automated FT-IR screening method for cocaine identification in seized drug samples Authors

Rapid classification and quantification of cocaine in seized powders with ATR-FTIR and chemometrics.

Traditionally, fast screening for the presence of cocaine in unknown powders is performed by means of colour tests. The major drawbacks of these tests are subjective colour evaluation depending on the operator ('50 shades of blue') and a lack of selectivity. An alternative fast screening technique is Fourier Transform InfraRed (FTIR) spectrometry. This technique provides spectra that are diffic...

Effect of Sample Complexity on Quantification of Analytesin Aqueous Samples by Near-Infrared Spectroscopy

hydrochlorothiazide detection in urine samples by hplc-dad and experimental design dispersive l-l microextraction

hydrochlorothiazide (hct) is a diuretic agent which is shown to be effective in the treatment of hypertension. literature reports have demonstrated that urinary excretion data may be used to assess the bioavailability of various formulations containing this thiazide. also hct consumption by the athletes is one of the drugs which should be regulated by world anti-doping agency (wada), because of...